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    Home » Recipes » Main Course

    Spinach and Artichoke Casserole with Ground Beef

    Modified: Jun 21, 2025 • Published: Jan 13, 2022 by Dr. Erin Carter • This post may contain affiliate links • 3 Comments

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    A bowl of spinach and artichoke casserole served over noodles.
    A bowl of spinach and artichoke casserole served over noodles.

    This spinach and artichoke casserole is the ultimate comfort food. With its rich and creamy sauce this healthy casserole is always a crowd pleaser. Made with fresh spinach, this recipe is also dairy-free, gluten-free, paleo, and Whole30 compliant.

    A white casserole dish filled with a creamy casserole filled with spinach and ground beef.

    Healthy ground beef recipes like my meatloaf without breadcrumbs or ketchup are some of my favourite to make, which is why I am so excited for you to try the ground beef casserole I am sharing with you today.

    Table of Contents
    • Why you will love this casserole:
    • Ingredients:
    • Recipe variations and add ins:
    • How to make this spinach and artichoke casserole:
    • Top Tips:
    • Spinach and artichoke casserole FAQs:
    • Other healthy meals you will love:
    • Recipe

    Why you will love this casserole:

    • The flavour! This healthy spinach and artichoke casserole is so delicious!
    • It's quick and easy to make and is a healthy, complete meal.
    • Not only is this casserole healthy, but it's also paleo, Whole30 compliant, dairy-free and gluten-free. But don't worry, it tastes so good that you will never be able to tell.

    Ingredients:

    For the full list of ingredients and exact measurements refer to the recipe card later in this post:

    Jump to Recipe
    Different foods in bowls including chopped onion, cashews, spinach, ground beef, coconut milk and spices.
    • Lean ground beef: I like to use grass fed and grass finished ground beef, but you can use any type of ground beef that you prefer. 
    • Raw cashews: these help make the delicious creamy sauce on this casserole. Be sure to use raw cashews and not roasted cashews.
    • Coconut milk: paired with the raw cashews, this helps give the sauce the perfect thick and creamy texture. I recommend using full fat coconut milk and not low fat coconut milk which is more watery.
    • Avocado oil: you could swap this for olive oil.
    • Onion: helps add even more flavour to this casserole. You can use white onion, yellow onion or sweet onion.
    • Nutritional yeast: a great dairy free option for achieving a cheesy texture in recipes, without using any cheese!
    • Canned artichoke hearts
    • Spinach: you can use either fresh spinach or frozen spinach for making this gluten-free casserole.
    • Seasonings and spices: sea salt and ground black pepper are the only spices you need.

    Recipe variations and add ins:

    • You can substitute the ground beef for ground turkey or ground chicken. 
    • You can add more vegetables to this recipe. I recommend mushrooms or green beans. 
    • To make this into a vegan casserole or a meatless casserole: omit the ground beef and use a vegan ground meat, or add more vegetables instead.

    How to make this spinach and artichoke casserole:

    A skillet with cooked ground beef in it.

    Step one: Preheat your oven to 350 degrees Fahrenheit and while it is preheating place a large pan or skillet on the stovetop on medium heat. Then add the oil and ground beef and cook the beef until it's browned, stirring frequently to break it apart.

    A baking dish with cooked ground beef in it.

    Step two: Once the beef is cooked, transfer it to a 9" x 13" baking dish and set it aside.

    A blender with cashews, milk, oil and chopped onion in it.

    Step three: make the cream sauce by placing the sauce ingredients in a high-speed blender.

    A blender with a creamy sauce in it.

    Step four: Blend the sauce ingredients until they are smooth. Then set the sauce aside.

    A pan with spinach and artichoke hearts in it.

    Step five: Using the same pan that you used to cook the beef, add the oil and chopped onion. Cook the onion for a few minutes until it's translucent. Then add the chopped artichoke hearts and spinach to the pan with the cooked onion. Cook until the spinach is wilted or no longer frozen.

    A pan with cooked spinach and artichoke hearts in it with a creamy sauce being poured over the vegetables.

    Step six: Add the sauce to the pan with the veggies and stir everything well to combine.

    A baking dish with cooked ground beef in it, partially covered by a creamy sauce.

    Step seven: Transfer the sauce to the casserole dish with the cooked ground beef and stir everything together to combine.

    A baking dish filled with a creamy ground beef casserole with spinach in it.

    Step eight: Bake uncovered in the oven for 10-15 minutes and then enjoy!

    Top Tips:

    • To prepare this casserole ahead of time: make and cook the casserole, then cover it in foil and store it in the fridge overnight. Then when you want to eat it, heat it at 350 degrees Fahrenheit for 10-15 minutes, until it's warmed through.
    • Serving ideas: this casserole is delicious served as is but you could serve it over cooked noodles or rice to make it even more filling and turn it into more of a classic casserole.
    • Storage: store any leftover casserole in the fridge in an airtight container for up to 5 days. 
    A bowl of spinach and artichoke casserole served over spiral noodles.

    Spinach and artichoke casserole FAQs:

    What can I use instead of cashews?

    While cashews are the best option for this recipe, macadamia nuts or pine nuts could be a good substitute for cashews.

    Can I use fresh artichokes for this casserole?

    You could use fresh artichokes for this recipe, just be sure to steam them first.

    Can I freeze this casserole? 

    Yes! This paleo ground beef casserole freezes really well for up to 3 months. 

    Is this casserole keto?

    No, this is not a low carb or keto casserole recipe.

    Other healthy meals you will love:

    • A bowl of Whole30 teriyaki chicken and broccoli with chopsticks in it.
      Whole30 Teriyaki Chicken and Broccoli
    • A pan with a cooked chicken dish in it in a red creamy sauce topped with fresh basil and chopped black olives.
      Dairy Free Sun-Dried Tomato Chicken with Spinach
    • A glass dish filled with a bacon and vegetable egg casserole.
      The Best Bacon and Vegetable Egg Casserole
    • A pan of cooked Whole30 stuffed peppers garnished with fresh parsley.
      Whole30 Stuffed Peppers (gluten-free, paleo)

    Since you made it this far we are basically best friends so be sure to follow me on Instagram, Pinterest, TikTok and Facebook where I share even more recipes and healthy living tips! And don’t forget to leave this recipe a star review before you go!

    Recipe

    A bowl of spinach and artichoke casserole over noodles.

    Spinach and Artichoke Casserole

    This spinach and artichoke casserole is the perfect comfort food. Rich and creamy this healthy dinner will be a hit with the whole family.
    4.92 from 12 votes
    Print Pin Rate
    Course: Main Course, Meat
    Cuisine: American
    Diet: Diabetic, Gluten Free, Low Lactose
    Prep Time: 5 minutes minutes
    Cook Time: 25 minutes minutes
    Total Time: 30 minutes minutes
    Servings: 8
    Calories: 705kcal
    Author: Dr. Erin Carter

    Equipment

    • Skillet or pan
    • 9" x 13" baking dish

    Ingredients

    • 2 tablespoon avocado oil (or other cooking oil of choice)
    • 2 lbs ground beef

    Cream Sauce Ingredients

    • 2 cups raw cashews
    • 1 1/4 cups coconut milk
    • 1/4 cup avocado oil
    • 2 tablespoon lemon juice
    • 1 small white or yellow onion, chopped
    • 1/3 cup nutritional yeast
    • 2 cloves garlic, minced
    • 1 1/2 teaspoon sea salt (more or less to taste)
    • 1 teaspoon ground black pepper (more or less to taste)

    Spinach and Artichoke Ingredients

    • 3 tablespoon avocado oil (or other cooking oil of choice)
    • 1/2 onion, chopped
    • 1 can artichoke hearts, drained and chopped (24 ounces)
    • 300 grams fresh or frozen chopped spinach (10 ounces)

    Instructions

    • Preheat your oven to 350F.
    • Place a large pan on the stove on medium heat, add the avocado oil and ground beef and cook the beef until browned, stirring frequently to break up the beef. Once the beef is done cooking, transfer it to a 9" x 13" casserole or baking dish and set it aside.
    • While the beef is cooking, make the cream sauce by placing all the ingredients into your high speed blender and blending until smooth. Set the sauce aside.
    • Using the same pan that you used to cook the beef, add the avocado oil and onion, and cook the onion for a few minutes on medium heat until it's translucent.
    • Add the chopped artichoke hearts and spinach to the pan with the onion and cook for a few more minutes, until the spinach is wilted or no longer frozen (depending on if you are using fresh or frozen spinach).
    • Add the sauce to the pan and stir all the ingredients well to combine.
    • Transfer the sauce to the casserole dish with the ground beef and stir everything well to combine. Bake the dish in the oven for 10-15 minutes, until warmed throughout.

    Notes

    1. Nutritional values are an estimate and will vary depending on the exact ingredients used and your serving size.
    2. Store this casserole in an airtight container in the fridge for up to 5 days.

    Nutrition

    Calories: 705kcal | Carbohydrates: 16g | Protein: 29g | Fat: 60g | Saturated Fat: 20g | Polyunsaturated Fat: 5g | Monounsaturated Fat: 29g | Trans Fat: 1g | Cholesterol: 81mg | Sodium: 662mg | Potassium: 876mg | Fiber: 3g | Sugar: 3g | Vitamin A: 3518IU | Vitamin C: 14mg | Calcium: 82mg | Iron: 7mg
    Tried this Recipe? Pin it for Later!Mention @pureandsimpleno or tag #pureandsimpleno!

    DISCLAIMERS: The statements made on this website have not been approved by the Food and Drug Administration or Health Canada. The information is not intended to diagnose, treat, cure, or prevent disease. You assume full responsibility for how you use this information. Always consult with your physician or other health professionals before making any diet or lifestyle changes. This post may contain affiliate links whereby if you purchase these products I receive a small percentage of the sale price. This allows me to keep the blog running and I thank you for allowing me to do that!

    Reader Interactions

    Comments

    1. Kristine

      July 06, 2025 at 10:18 pm

      Oh….my…….gah!!!!! I am a good cook, a great cook even….but I was burnt out so I came across this recipe on Pinterest and knew it sounded fire…..but let me tell you. It was even better than I could imagine! I mis-read the artichoke hearts and fell short of 24 ounces so I had to improvise and use an extra jar of marinated grilled artichokes with my 10oz jar -rinsed of course and this is so good. Thank you for sharing this. You absolutely have a new fan right here.

      Reply
    2. Justin

      April 02, 2025 at 2:44 pm

      did you not find that the coconut milk overwhelmed the whole dish and kind of ruined the savory flavoring?

      Reply
      • Dr. Erin Carter

        April 10, 2025 at 9:10 am

        Hi! No I didn't find that.

        Reply

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    My name is Dr. Erin Carter and I am so thrilled you are here. I am a physician with specialties in both internal medicine and rheumatology, and I believe that food and healthy living are forms of medicine. In my spare time I share health information and delicious, healthy recipes here on Pure and Simple Nourishment.

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