Preheat your oven to 350F.
Place a large pan on the stove on medium heat, add the avocado oil and ground beef and cook the beef until browned, stirring frequently to break up the beef. Once the beef is done cooking, transfer it to a 9" x 13" casserole or baking dish and set it aside.
While the beef is cooking, make the cream sauce by placing all the ingredients into your high speed blender and blending until smooth. Set the sauce aside.
Using the same pan that you used to cook the beef, add the avocado oil and onion, and cook the onion for a few minutes on medium heat until it's translucent.
Add the chopped artichoke hearts and spinach to the pan with the onion and cook for a few more minutes, until the spinach is wilted or no longer frozen (depending on if you are using fresh or frozen spinach).
Add the sauce to the pan and stir all the ingredients well to combine.
Transfer the sauce to the casserole dish with the ground beef and stir everything well to combine. Bake the dish in the oven for 10-15 minutes, until warmed throughout.